Design principles for accurate folding of DNA origami. T Aksel, EJ Navarro, N Fong, SM Douglas (2024) preprint – colab

Engineering an Escherichia coli strain for production of long single-stranded DNA. K Shen, JJ Flood, Z Zhang, A Ha, BR Shy, JE Dueber, SM Douglas (2024) Nucleic Acids Res. 52(7) 4098–4107 pdf –  preprint –  pubmed –  publisher

Tight nanoscale clustering of Fcγ-receptors using DNA origami promotes phagocytosis. N Kern, R Dong, SM Douglas, RD Vale, MA Morrissey (2021) eLife. pdf – preprint – pubmed – publisher

DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation. R Dong, T Aksel, W Chan, RN Germain, RD Vale, SM Douglas (2021) PNAS. 118 (40) e2109057118 pdf – preprint – pubmed – publisher

Molecular goniometers for single-particle cryo-EM of DNA-binding proteins. T Aksel, Z Yu, Y Cheng, SM Douglas (2020) Nat Biotechnol. 39: 378–386pdf – preprint – pubmed – publisher

Amino and PEG-amino graphene oxide grids enrich and protect samples for high-resolution single particle cryo-electron microscopy. F Wang, Z Yu, M Betegon, M Campbell, T Aksel, J Zhao, S Li, SM Douglas, Y Cheng, DA Agard (2019) J Struct Biol. 209:107437. preprint – pubmed – publisher

Gelbox - An Interactive Simulation Tool for Gel Electrophoresis. C Gingold, SM Douglas (2018) preprint – website

Construction of a novel phagemid to produce custom DNA origami scaffolds. PM Nafisi, T Aksel, SM Douglas (2018) Synthetic Biology. ysy015 pdf – preprint – publisher

Perspective: Bringing proteins into the fold. SM Douglas (2017) Science. 355:1261–2 pdf – pubmed – publisher

Folding complex DNA nanostructures from limited sets of reusable sequences. S Niekamp, K Blumer, PM Nafisi, K Tsui, J Garbutt, SM Douglas (2016) Nucleic Acids Res. 44:e102 pdf – pubmed – publisher

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads. SM Douglas, I Bachelet, GM Church (2012) Science. 335:831–4 pdf – pubmed – publisher

Multilayer DNA Origami Packed on a Square Lattice. Y Ke, SM Douglas, M Liu, J Sharma, A Cheng, A Leung, Y Liu, WM Shih, H Yan. (2009) JACS. 131: 15903-8 pdf – pubmed – publisher

Folding DNA Into Twisted and Curved Nanoscale Shapes. H Dietz, SM Douglas, WM Shih (2009) Science. 325:725–730 pdfpubmedpublisher

Rapid Prototyping of Three-Dimensional DNA-Origami Shapes With caDNAno. SM Douglas, AH Marblestone, S Teerapittayanon, A Vazquez, GM Church, WM Shih (2009) Nucleic Acids Res. 37:5001–6 pdf – pubmed – publisher – website

Self-Assembly of DNA Into Nanoscale Three-Dimensional Shapes. SM Douglas, H Dietz, T Liedl, B Högberg, F Graf, WM Shih (2009) Nature. 459:414–8 pdfpubmedpublisher

DNA-Nanotube-Induced Alignment of Membrane Proteins for NMR Structure Determination. SM Douglas, JJ Chou, WM Shih (2007) PNAS 104:6644–8 pdfpubmedpublisher

For older publications, visit this page.

University of California, San Francisco

Dept. of Cellular and Molecular Mad Science
Mission Bay — Genentech Hall